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The PlantsP and PlantsT Functional Genomics Databases

机译:PlantsP和PlantsT功能基因组学数据库

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摘要

PlantsP and PlantsT allow users to quickly gain a global understanding of plant phosphoproteins and plant membrane transporters, respectively, from evolutionary relationships to biochemical function as well as a deep understanding of the molecular biology of individual genes and their products. As one database with two functionally different web interfaces, PlantsP and PlantsT are curated plant-specific databases that combine sequence-derived information with experimental functional-genomics data. PlantsP focuses on proteins involved in the phosphorylation process (i.e., kinases and phosphatases), whereas PlantsT focuses on membrane transport proteins. Experimentally, PlantsP provides a resource for information on a collection of T-DNA insertion mutants (knockouts) in each kinase and phosphatase, primarily in Arabidopsis thaliana, and PlantsT uniquely combines experimental data regarding mineral composition (derived from inductively coupled plasma atomic emission spectroscopy) of mutant and wild-type strains. Both databases provide extensive information on motifs and domains, detailed information contributed by individual experts in their respective fields, and descriptive information drawn directly from the literature. The databases incorporate a unique user annotation and review feature aimed at acquiring expert annotation directly from the plant biology community. PlantsP is available at http://plantsp.sdsc.edu and PlantsT is available at http://plantst.sdsc.edu.
机译:通过PlantsP和PlantsT,用户可以快速地全面了解植物磷蛋白和植物膜转运蛋白,从进化关系到生化功能,以及对单个基因及其产物的分子生物学的深刻理解。作为一个具有两个功能不同的Web界面的数据库,PlantsP和PlantsT是精心挑选的植物特定数据库,将序列信息与实验功能基因组学数据相结合。 PlantsP专注于参与磷酸化过程的蛋白(即激酶和磷酸酶),而PlantsT专注于膜转运蛋白。在实验上,PlantsP提供了一种资源,可用于获取有关每种激酶和磷酸酶(主要在拟南芥中)的T-DNA插入突变体(敲除)的信息,并且PlantsT独特地结合了有关矿物成分的实验数据(来自感应耦合等离子体原子发射光谱法)突变株和野生株。这两个数据库均提供有关主题和领域的广泛信息,由各自领域的专家提供的详细信息以及直接从文献中获得的描述性信息。该数据库具有独特的用户注释和审阅功能,旨在直接从植物生物学界获取专家注释。 PlantsP可以从http://plantsp.sdsc.edu获得,PlantsT可以从http://plantst.sdsc.edu获得。

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